The role and efficacy of catecholamines

As the saying goes, western medicines have quick effects, but the side effects are worrying. Chinese medicines will weaken their efficacy during our own cooking process, while proprietary Chinese medicines neutralize the two and achieve very good treatment effects. Among them, catecholamines are one of them. Chinese patent medicine, it is a neurological substance containing catechol and amine groups. What are the functions and effects of catecholamines? Catechols and amine groups are combined through the enzymatic step of L-tyrosine in sympathetic nerves, adrenal medulla and chromaffin cells; generally, catecholamines refer to norepinephrine (NA), adrenaline (Adr) and dopamine (DA), these three catecholamines are all converted from tyrosine as a precursor.

The role and efficacy of catecholamines

Clinical application:

1. Shock, dopamine is commonly used in the early stage of neurogenic, cardiogenic, and septic shock to enhance myocardial contractility and expand peripheral blood vessels to improve microcirculation. Adrenaline is commonly used for anaphylactic shock.Dopamine anti-shock agent

The amount should not be too large. Generally, 2 mg is added to 500 ml of 5% glucose, and the intravenous infusion rate is controlled at 4-8 micrograms per minute to maintain the systolic blood pressure at about 90mmHg.

2. Stomach bleeding. Dilute with 1-3 mg of catecholamine and take it orally. It will produce hemostatic effect due to local contraction of gastric mucosal blood vessels in the stomach.

The adverse reaction is: local tissue ischemic necrosis may occur; so do not let the medicine leak out of the blood vessel. Do not use too large a dose; so as to avoid acute renal failure. In addition, a sudden stop of the drug may cause a drop in blood pressure. When the drug needs to be discontinued, the dose should be gradually reduced and the drip rate should be gradually reduced, and then the drug should be discontinued.

Adverse reactions

Local tissue ischemic necrosis can occur, so do not let the medicine leak out of the blood vessel. The dose should not be too large to avoid acute renal failure. In addition, a sudden stop of the drug may cause a drop in blood pressure. When the drug needs to be discontinued, the dose should be gradually reduced and the drip rate should be gradually reduced, and then the drug should be discontinued.

Precautions

Patients suffering from hypertension, arteriosclerosis and anuria are contraindicated.

Contraindications

It should be used with caution in shock patients with hypertension, coronary heart disease, arteriosclerosis, heart failure, hyperthyroidism, diabetes, severe renal insufficiency, and microcirculation disorders, the elderly and pregnant women.

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